Title
The Effects of Cholesterol on Lipid Bilayers
Document Type
Article
Publication Date
2002
Abstract
Differential scanning calorimetry (DSC) was used to study the effects of cholesterol on the thermotropic phase behavior of fully hydrated 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC). DPPC was studied with cholesterol ranging from 0 to 22 mol% cholesterol over a temperature range from 20 to 50?C. DSC studies show a decrease in the main transition temperature (Tm) for DPPC with concentrations of cholesterol increasing up to 12 mol%. However, at concentrations greater than 12 mol%, there is an increase in Tm for DPPC. The pre-transition for DPPC was also found to be diminished at cholesterol concentrations greater than 5 mol%.
Recommended Citation
Shin, Samuel, "The Effects of Cholesterol on Lipid Bilayers" (2002). URC Student Scholarship.
http://scholar.oxy.edu/urc_student/910
Advisor
P. Dea
Department
chem
Support
Support provided by:National Science Foundation-Research Experience for Undergraduates Fellowship
This document is currently not available here.