Browsing by Author "Yew, Margaret"

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Immunoglobulin Gene Rearrangement: Differential Signaling by a Transgenic Heavy Chain

Yew, Margaret (2002-01-01)

The HUG gene is a chimeric gene leading to the synthesis of a protein antibody of the gamma (g) isotype consisting of a mouse variable region and a human g1 constant region. In order to produce a functional antibody, gene ...
Immunoglobulin Gene Rearrangement: Differential Signaling By a Transgenic Heavy Chain.

Yew, Margaret (2001-01-01)

Our body is the milieu for an ongoing battle between pathogen and antibody. The diversity of these foreign substances called antigens number in the thousands. Each has unique epitopes that act as keys to which the antibody ...