Browsing Chemistry URC Student Scholarship by Issue Date
Now showing items 1-20 of 276
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Studies directed towards the Synthesis of Enantio-enriched a,b-Unsaturated Imidates and their Application in a Cyclic Intermediate [3,3]-Sigmatropic Shift Summer Collier and Caroline Carter
(1999-01-01)The overarching goal of this research is the development of synthetic methodologies that permit facile, enantiocontrolled access to molecules of biological importance, more specifically, imidate (1) derived from enantiomerically ... -
Synthesis of Enantiopure a,b-Unsaturated Cyanohydrins using Enzyme Technology.
(1999-01-01)For years pharmaceutical companies have struggled with the side effects caused by racemic mixtures of pharmaceutical drugs. The most noted example is Thalidomide, a drug marketed widely throughout Europe in the 1960's. The ... -
A Two-step Method for the Conversion of a.b-Unsaturated Aldehydes into g-Azido-a,b-Unsaturated Nitriles. Sanaz Tafti, Henry Kim & Cullen Tanaguchi
(1999-01-01)g-Azido-a,b-unsaturated nitriles are important synthetic intermediates due to their versatility as precursors to many diverse organic compounds. We have developed a fast, convenient and efficient two-step method for ... -
Preparation of Two-Dimensional Arrays of Ag Nanopaticles for Laser Interrogation.
(1999-01-01)A nanoparticle is a collection of thousands of atoms in a typically spherical shape with a diameter of 1 to 100 nm. These particles are bits of matter that lie somewhere between the atom and the bulk. Their chemical and ... -
Structure and Dynamics of DNA Condensates at the Solid-Liquid Interface.
(1999-01-01)To better understand the packaging of deoxyribonucleic acid (DNA) in the cell, plasmid DNA is imaged under fluid using atomic force microscopy. DNA condensates are formed at the solid-liquid interface of aqueous buffer and ... -
Pulsed Laser Deposition of Metal-containing Films on Supported Self-assembled Monolayers.
(1999-01-01)A diffusion-pumped, high vacuum system was built for pulsed laser deposition studies. A variety of metal-containing films deposited on self-assembled monolayers (SAMs) have been and will be studied in order to elucidate ... -
Electrochemistry, Photophysics and Spectroscopy of a New Class of Electron Transfer Quenchers. Crisjoe Joseph & Azam Ahmed
(1999-01-01)A quencher provides two additional routes for the excited species to return to the ground state: energy transfer and electron transfer. This project looks at ruthenium compounds that do not absorb at these high wavelengths ... -
Multiple-Electron Transfer Complexes Using Ferrocene Derivatives as Ligands.
(1999-01-01)Our research is directed toward the design of catalysts capable of multi-electron transfer required for the development of photosynthetic systems and fuel cells. One of the biggest challenges that chemists face today is ... -
Electrochemically Triggered Protein Unfolding. Melanie Koch and Esther Moran
(1999-01-01)Cyclic voltammetry has been used to study the unfolding dynamics of a redox-active heme protein, cytochrome b562 (cyt b562). Oxidized cyt b562 unfolds upon oxidation of folded, reduced cyt b562 in the presence of high ... -
A Supramolecular Assembly for Solar-Energy Storage
(1999-01-01)Our research is directed toward the solar-energy conversion of water to molecular hydrogen. A cheap method of producing H2 would not only provide an abundant energy source, but would also alleviate many of the environmental ... -
NMR Studies of Fatty Acids and Phospholipids.
(1999-01-01)A balloon technique was used to hydrogenate 9-octadecenoic acid (oleic acid) and deuterate dipalmitoleoylphosphatidylcholine, a 16-carbon acyl chain phospholipid with unsaturation at the 9,10 position. This technique ... -
Chlorpromazine Hydrochloride Micellization and the Thermodynamics of Aggregation in Aqueous Solution.
(1999-01-01)The mean aggregate number (MAN) of the antipsychotic drug chlorpromazine hydro-chloride (CPZ) was investigated by fluorescence quenching. Using the intrinsic fluorescent properties of CPZ micelles and the quenching effect ... -
Thermotropic Properties of Dimyristoylphosphatidylcholine Bilayers Shirleen SM Ho and Henry H. Chang
(1999-01-01)Cholesterol was incorporated into DMPC to better mimic the biological membrane. It was elucidated that formation of the stable DMPC subgel phase is a complex process that demonstrates the metastability of the planar gel ... -
Subgel Studies of Dimyristoylphosphatidylcholine Bilayers.
(1999-01-01)When bilayers of some saturated PCs are stored for three or more days at ~273 K, a lamellar subgel phase has been detected at temperatures below the pre-transition by differential scanning calorimetry (DSC). However, the ... -
The Interactions between Dipalmitoylphosphatidylcholine and Chlorpromazine Hydrochloride.
(1999-01-01)The interactions between dipalmitoylphosphatidylcholine (DPPC) and the tranquilizer, chlorpromazine hydrochloride (CPZ), were studied using isothermal titration calorimetry. Results showed that the heats of interaction ... -
FTIR Spectroscopy of Heat Treated Sol-Gels.
(1999-01-01)Acid catalyzed sol-gels, which have not been thoroughly washed to remove residual solvent, change from a colorless gel to a black xerogel upon being heated to high temperatures ~900 degrees Celsius. The darkening of the ... -
FTIR Analysis of Sol-Gel Encapsulated Proteins.
(1999-01-01)FTIR spectroscopy was used to study the effects of sol-gel encapsulation on the secondary structure of the guest proteins. Gel samples were prepared as KBr pellets and the spectrum of a blank gel was subtracted from that ... -
A Study of Soluble Glucose Dehydrogenase Based upon Kinetic Studies of the Structural Analogs of PQQ. James Ewing, Leslie Thompson & Carolnn Yong
(1999-01-01)Soluble glucose dehydrogenase is a homodimeric enzyme found in various bacteria such as Acinetobacter calcoaceticus , requiring Ca<sup>2+</sup> and pyrroloquinolinequinone (PQQ) cofactors for full enzymatic activity. sGDH ... -
The Effects of Illumination onthe Oxidation Reactions of PQQ. Lousine Boyadzhyan & Alicia McCarthy
(1999-01-01)PQQ, formally known as 2,7,9-tricarboxy-1H-pyrrolo [2,3-f] quinoline-4,5-dione, exists as an enzyme cofactor in bacterial methanol and glucose dehydrogenases. Since its discovery in 1979, the reactivity of PQQ has attracted ... -
Characterization of Coal using FTIR Spectroscopy: Aromaticity and Coal Rank.
(1999-01-01)The study of coal composition and structure has long depended on Fourier Transform Infrared Spectroscopy, and curve-fitting analysis of such spectra can offer additional information. Eight coals from the Argonne National ...