• Login
    View Item 
    •   Oxy Scholar Home
    • Biochemistry
    • Biochemistry URC Student Scholarship
    • View Item
    •   Oxy Scholar Home
    • Biochemistry
    • Biochemistry URC Student Scholarship
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    The Development and Characterization of Polyvalent Anti-Influenza Antivirals

    Thumbnail
    Author
    Hong, Kevin
    Issue
    urc_student; urc_student
    Date
    2012-07-01 0:00
    Metadata
    Show full item record
    URI
    https://scholar.oxy.edu/handle/20.500.12711/307
    Abstract
    The influenza virus infects host cells via the collective interaction (polyvalence) between many hemagglutinin (HA) sites, which are glycoproteins found on the viral envelope, and sialic acid (SA) residues found on the membrane of the host cell. Therefore, a proposed antiviral targeting influenza would have to also react polyvalently for optimal performance, for which we propose the Q-Beta virus as a bacteriophage scaffold. We have introduced mutations that should allow for the introduction of unnatural amino acids that will serve as sites for the attachment of sugars that will alter protein expression, causing the Q-Beta virus to bind and inhibit influenza.
    Collections
    • Biochemistry URC Student Scholarship

    Browse

    All of Oxy ScholarCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsJournal TitleJournal IssueThis CollectionBy Issue DateAuthorsTitlesSubjectsJournal TitleJournal Issue

    My Account

    LoginRegister

    DSpace software copyright © 2002-2021  DuraSpace
    Contact Us | Send Feedback
    DSpace Express is a service operated by 
    Atmire NV