• Login
    View Item 
    •   Oxy Scholar Home
    • Chemistry
    • Chemistry URC Student Scholarship
    • View Item
    •   Oxy Scholar Home
    • Chemistry
    • Chemistry URC Student Scholarship
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Effects of 1-Pentanol and 2-Pentanol on Phospholipid Bilayer Membranes

    Thumbnail
    Author
    Cheng, Chih-Yin
    Issue
    urc_student; urc_student
    Date
    2006-01-01 0:00
    Metadata
    Show full item record
    URI
    https://scholar.oxy.edu/handle/20.500.12711/705
    Abstract
    The effects of varied concentration of 1-pentanol and 2-pentanol on the phase transitions of dipalmitoylphosphatidycholine (DPPC) bilayers were studied using differential scanning calorimetry (DSC). The threshold concentrations for 1-pentanol and 2-pentanol to induce the interdigitated phase were observed to be at about 0.06mM and 0.1mM respectively. These critical concentrations were indicated by the disappearance of the pre-transition and an increasing hysteresis between the main transition temperatures of the heating and cooling scans. At concentrations lower than the threshold, the main transition temperature decreased with increasing concentration for both 1- and 2-pentanol; however, the behavior of the main transition temperature in 1- and 2-pentanol differed slightly at concentrations higher than the threshold. Neither of the isomers demonstrated the biphasic effect, but did show a change in slope of the main transition temperature. At concentrations higher than the threshold, the main transition temperatures of DPPC in 1-pentanol did not increase with increasing concentration, while that of DPPC in 2-pentanol clearly increased but in a small concentration range. Both isomers showed a decrease in the main transition temperature at higher pentanol concentrations. The observed difference in the threshold concentrations implied that branching decreased its effectiveness in inducing the interdigitated phase in DPPC.
    Collections
    • Chemistry URC Student Scholarship

    Browse

    All of Oxy ScholarCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsJournal TitleJournal IssueThis CollectionBy Issue DateAuthorsTitlesSubjectsJournal TitleJournal Issue

    My Account

    LoginRegister

    DSpace software copyright © 2002-2021  DuraSpace
    Contact Us | Send Feedback
    DSpace Express is a service operated by 
    Atmire NV