Show simple item record

dc.contributor.advisorOtsuki, Testuo
dc.contributor.authorWoertink, Jason
dc.date.accessioned2020-08-13T14:56:00Z
dc.date.available2020-08-13T14:56:00Z
dc.date.issued1999-01-01 0:00
dc.identifier.urihttps://scholar.oxy.edu/handle/20.500.12711/716
dc.description.abstractQuinones undergo a variety of photochemical reactions. Quinoline-5,8-diones are expected to have photochemical reactivity. I synthesized quinoline-5,8-dione and its 2-methyl derivative. They were found to react with a variety of aldehydes under irradiation. An addition product was isolated as a major product of the photochemical reaction. The reactivity of PQQ, a coenzyme of soluble glucose dehydrogenase, is increased by illumination. As suggested through the study of methanol dehydrogenase, Ca<sup>2+</sup> ion is expected to form a complex with PQQ at its 5-carbonyl, 6-nitrogen atom, and 7-carboxylic acid group. Quinoline-5,8-dione derivatives have been reported to complex at the 1-nitrogen atom, and 8-carbonyl group. Given quinoline-5,8-dione&#146;s photochemical and metal ion binding potential a 2-carboxylic acid derivative of quinoline-5,8-dione is expected to be an effective model of PQQ.
dc.description.sponsorshipNational Science Foundation-AIRE, Monsanto Foundation, Occidental College Academic Support Program
dc.titleSynthesis of Quinoline-5,8-diones as a Model of PQQ and Its Photochemical Reactivity.
dc.typearticle
dc.abstract.formathtml
dc.description.departmentchem
dc.source.issueurc_student
dc.source.issueurc_student
dc.identifier.legacyhttps://scholar.oxy.edu/urc_student/1129
dc.source.statuspublished


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record